Thermo Fisher Scientific PKD1 Polyclonal Antibody
PKD1 단백질을 인식하는 Rabbit Polyclonal Antibody로 인간 시료에 반응합니다. Western blot과 IHC에 사용 가능하며, 합성 펩타이드 항원으로 제작되었습니다. 장기 보관 시 -20°C에서 보관하며 연구용으로만 사용됩니다.
- 판매단위
- pk
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Applications
- Western Blot (WB): 1:1,000
- Immunohistochemistry (IHC): 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from human PKD1 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: PKD1
Target Information
PKD1 is involved in renal tubulogenesis and fluid-flow mechanosensation by the primary cilium in renal epithelium. It acts as a regulator of cilium length together with PKD2, contributing to mechanotransductive signaling regulation. The cilium length response forms a negative feedback loop where fluid shear-mediated deflection decreases intracellular cAMP, leading to cilium shortening and reduced flow-induced signaling. PKD1 may also function as an ion-channel regulator and participate in adhesive protein-protein and protein-carbohydrate interactions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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