Thermo Fisher Scientific NEUROG1 Monoclonal Antibody (OTI19A11), TrueMAB
NEUROG1 단백질을 인식하는 마우스 단클론 항체로, Western blot, IHC, IP 등에 사용 가능. 인간 시료 반응성. 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도 유지. 신경발생 연구 및 세포 분화 조절 기전 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunoprecipitation (IP) | 2–4 µg/mg |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI19A11 |
| Immunogen | Full length human recombinant protein of human NEUROG1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, it is recommended to perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Neurogenin 1 (NEUROG1) is a basic helix-loop-helix (bHLH) transcription factor involved in cell fate determination during development.
NeuroG1 functions in neurogenesis and inhibits differentiation of neural stem cells into astrocytes.
It promotes neuronal differentiation by acting as a transcriptional activator and inhibits astrocyte differentiation by sequestering CREB-binding protein transcription complexes and suppressing STAT transcription factors essential for gliogenesis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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