Thermo Fisher Scientific CYP2A6 Monoclonal Antibody (OTI5F8), TrueMAB
인간 CYP2A6 단백질을 인식하는 단일클론 항체로, WB, IHC, ICC, Flow Cytometry에 사용 가능. TrueMAB 형식으로 높은 특이성과 재현성 제공. 동결건조 형태로 안정적이며, 연구용으로 적합.
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Thermo Fisher Scientific CYP2A6 Monoclonal Antibody (OTI5F8), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5F8 |
| Immunogen | Full length human recombinant protein of human CYP2A6 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
CYP2A6 encodes a cytochrome P450 enzyme involved in drug metabolism and lipid synthesis.
This protein localizes to the endoplasmic reticulum and is induced by phenobarbital.
It hydroxylates coumarin and metabolizes nicotine, aflatoxin B1, nitrosamines, and certain pharmaceuticals.
Variants of CYP2A6 may result in poor metabolizer phenotypes.
This gene is part of the CYP2A, CYP2B, and CYP2F subfamily cluster on chromosome 19q.
Previously referred to as CYP2A3, it has been renamed CYP2A6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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