Thermo Fisher Scientific Adiponectin Monoclonal Antibody (OTI1B2), TrueMAB
Adiponectin 단백질을 인식하는 인간 반응성 마우스 단클론 항체로, WB, IHC, ICC, Flow Cytometry에 사용 가능. TrueMAB 형식의 고순도 항체로, 동결건조 형태이며 트레할로스 포함 PBS buffer에 저장. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 19–244 of human ADIPOQ produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Adiponectin is a protein hormone secreted exclusively by adipocytes that regulates lipid and glucose metabolism. It plays roles in homeostasis and obesity. Decreased adiponectin levels are linked to obesity, insulin resistance, and type 2 diabetes. In mice, adiponectin enhances insulin signaling and reduces intramyocellular lipid levels through activation of AMP kinase and PPAR-alpha, improving metabolic function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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