Thermo Fisher Scientific HARS2 Monoclonal Antibody (OTI2D6), TrueMAB
HARS2 단백질을 인식하는 Mouse IgG1 단일클론 항체로, WB, IHC, Flow Cytometry에 최적화되어 있습니다. 인간 시료 반응성이 높으며, 동결건조 형태로 제공되어 안정적 보관이 가능합니다. 연구용으로 단백질 합성 및 Perrault 증후군 관련 연구에 활용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D6 |
| Immunogen | Full length human recombinant protein of human HARS2 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, it is recommended to perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Aminoacyl-tRNA synthetases are enzymes that charge tRNAs with their cognate amino acids. The HARS2 gene encodes a class II aminoacyl-tRNA synthetase involved in histidyl-transfer RNA synthesis and protein biosynthesis regulation.
Located in a head-to-head orientation with HARS on chromosome 5, the genes share a bidirectional promoter. Mutations in HARS2 are linked to Perrault syndrome, characterized by ovarian dysgenesis and sensorineural hearing loss.
Alternative splicing produces multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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