Thermo Fisher Scientific RAB23 Monoclonal Antibody (OTI2A8), TrueMAB
RAB23 단백질을 인식하는 Mouse monoclonal antibody로 Western blot과 IHC(Paraffin)에 적합. Human 시료 반응성. 고순도 Affinity chromatography 정제. PBS/BSA/glycerol buffer에 보관하며 -20°C에서 안정적 저장 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2A8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–234 of human RAB23 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The Ras-related superfamily of guanine nucleotide binding proteins includes the R-Ras, Rap, Ral/Rec, and Rho/Rab subfamilies. Rab proteins are essential in endocytosis and biosynthetic protein transport, mediating movement of vesicles from the endoplasmic reticulum through the Golgi complex to secretory vesicles.
Rab23 (also known as HSPC137) is a 237 amino acid protein localized to the cytoplasmic side of the cell membrane. It is involved in intracellular protein transportation and small GTPase-mediated signal transduction.
Mutations in the RAB23 gene are associated with Carpenter syndrome (ACPS2), characterized by obesity, cardiac defects, polysyndactyly, and craniosynostosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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