Thermo Fisher Scientific PRAME Monoclonal Antibody (CL5148)

Applications

Tested Dilution

Publications

Western Blot (WB)

1 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

CL5148

Immunogen

Recombinant protein corresponding to Human PRAME if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PRAME,uniProtId:P78395-1,ncbiNodeId:9606,antigenRange:265-390,antigenLength:509,antigenImageFileName:MA5-31409_PRAME_P78395-1_House_mouse.svg,antigenImageFileNamePDP:MA5-31409_PRAME_P78395-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2787045

Product Specific Information

Immunogen sequence: LLLSHIHASS YISPEKEEQY IAQFTSQFLS LQCLQALYVD SLFFLRGRLD QLLRHVMNPL ETLSITNCRL SEGDVMHLSQ SPSVSQLSVL SLSGVMLTDV SPEPLQALLE RASATLQDLV FDECGI

Target Information

This gene encodes an antigen that is predominantly expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. This expression pattern is similar to that of other CT antigens, such as MAGE, BAGE and GAGE. However, unlike these other CT antigens, this gene is also expressed in acute leukemias. Five alternatively spliced transcript variants encoding the same protein have been observed for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.