Thermo Fisher Scientific PARN Monoclonal Antibody (OTI2D3), TrueMAB
PARN 단백질을 인식하는 Mouse Monoclonal Antibody로, Western Blot에 최적화되어 있습니다. Human 시료에 반응하며, 1 mg/mL 농도의 액상 형태로 제공됩니다. Affinity chromatography로 정제되었으며, 안정적인 보관을 위해 -20°C에서 보관합니다.
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Applications
Tested Application
- Western Blot (WB)
Recommended Dilution
- 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–266 of human PARN produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by the PARN gene is a 3'-exoribonuclease with similarity to the RNase D family of 3'-exonucleases. It preferentially degrades poly(A) tails of mRNAs, initiating the decay of eukaryotic mRNAs. This protein also plays roles in silencing maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated mRNA decay (NMD). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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