Thermo Fisher Scientific PARN Monoclonal Antibody (OTI4C9), TrueMAB
PARN 단백질을 인식하는 Mouse monoclonal antibody로, Western blot 및 IHC(Paraffin)에서 사용 가능. Human 시료에 반응하며, Affinity chromatography로 정제됨. 1 mg/mL 농도의 액상 형태로 제공되며, -20°C에서 보관.
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Applications
- Western Blot (WB): 1:2,000
- Immunohistochemistry (Paraffin) (IHC (P)): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4C9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–266 of human PARN produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a 3′-exoribonuclease with similarity to the RNase D family of 3′-exonucleases. It preferentially degrades poly(A) tails of mRNAs, initiating eukaryotic mRNA decay. PARN is also involved in silencing maternal mRNAs during oocyte maturation and early embryonic development, as well as nonsense-mediated mRNA decay (NMD). Alternative splicing results in multiple isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송 정보
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