Thermo Fisher Scientific CSNK1E Monoclonal Antibody (OTI2B3), TrueMAB

Applications

• Western Blot (WB): Tested dilution 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

CSNK1E (CK1 epsilon) is a serine/threonine kinase involved in diverse cellular processes, including vesicular trafficking, DNA damage repair, cell cycle progression, and cytokinesis.
It phosphorylates key regulatory proteins controlling cell differentiation, proliferation, chromosome segregation, circadian rhythms, and metabolic pathways.
CK1 family members share a conserved kinase domain but differ in their variable N- and C-terminal regions. Mammals possess seven family members: alpha, beta, gamma1, gamma2, gamma3, delta, and epsilon.
CK1ε positively regulates Akt by inhibiting PP2A and plays a significant role in neurodegenerative disease mechanisms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.