Thermo Fisher Scientific TRIM72 Polyclonal Antibody
TRIM72 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human 시료에 반응하며 WB에 사용 가능. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 안정성을 제공. 세포막 손상 복구 관련 연구에 적합.
- 카탈로그번호
- PA531233
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment corresponding to a region within amino acids 82–258 of Human TRIM72 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2548707 |
Product Specific Information
- Recommended positive controls: HCT116
- Predicted reactivity: Mouse (93%), Rat (94%), Rabbit (96%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. Specifically binds phosphatidylserine. Acts as a sensor of oxidation: upon membrane damage, entry of extracellular oxidative environment results in disulfide bond formation and homooligomerization at the injury site. This oligomerization acts as a nucleation site for recruitment of TRIM72-containing vesicles to the injury site, leading to membrane patch formation. Probably acts upstream of the Ca(2+)-dependent membrane resealing process. Required for transport of DYSF to sites of cell injury during repair patch formation. Regulates membrane budding and exocytosis. May be involved in the regulation of the mobility of KCNB1-containing endocytic vesicles.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: PA5-31233_TRIM72_Q6ZMU5-1_Rabbit_PDP.jpeg, PA5-31233_TRIM72_Q6ZMU5-1_Rabbit.svg)
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