Thermo Fisher Scientific GBP5 Polyclonal Antibody
Thermo Fisher GBP5 폴리클로날 항체는 인간 GBP5 단백질을 인식하는 Rabbit IgG 항체로, Western blot과 IHC(Paraffin)에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 0.1M Tris-Glycine 버퍼에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 235–523 of Human GBP5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.66 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris Glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2548710 |
Product Specific Information
- Recommended positive control: HeLa cells
- Store as a concentrated solution. Centrifuge briefly before opening the vial.
Target Information
The guanylate-binding proteins (GBPs) are a family of interferon-induced GTP-binding proteins that function in innate immunity against microbial and viral pathogens.
In humans, seven GBPs (hGBP1–hGBP7) have been identified.
Human GBP1 and GBP2 exhibit antiviral activity and regulate endothelial cell proliferation and invasion in response to interferon (IFN).
GBP5 promotes selective NALP3 inflammasome responses to pathogenic bacteria and soluble, but not crystalline, inflammasome priming agents.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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