
Thermo Fisher Scientific Nestin Polyclonal Antibody
Rabbit polyclonal antibody targeting Nestin protein for WB and IHC applications. Useful for identifying stem/progenitor cells and tumor endothelial markers. Supplied as liquid form, 0.5 mg/mL, unconjugated. For research use only.
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Thermo Fisher Scientific Nestin Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 3–5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide (1484 ALETESQDSAEPSGSEE 1500) of Nestin protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2540909 |
Target Information
Nestin is a Class VI intermediate filament abundantly produced in the developing central nervous system (CNS) and in early embryonic neuroepithelial stem cells. It serves as a predominant marker for stem/progenitor cells, glioma cells, and tumor endothelial cells. Nestin is also a superior angiogenic marker used to evaluate neovascularity in tumor endothelial cells.
Highly specific antibodies to human Nestin assist in:
- Characterizing progenitor cells differentiating into distinct lineages
- Enhancing therapeutic potential of human neural stem/progenitor cells for CNS disease or injury
- Identifying neuroepithelial tumor cells
Nestin expression has been observed in pancreatic hematopoietic stem cell populations and is considered a novel angiogenesis marker of proliferating endothelial cells in colorectal cancer tissue.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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