Thermo Fisher Scientific PDZD2 Polyclonal Antibody
PDZD2 단백질을 검출하기 위한 Thermo Fisher Scientific의 토끼 폴리클로날 항체. IHC 및 ICC/IF 실험에 적합하며, 인간 시료에서 반응. 항원 친화 크로마토그래피로 정제된 액상 항체로, PBS와 글리세롤 버퍼에 보존되며 -20°C에서 저장.
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- PA549762
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:100
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from internal region of human PDZD2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635215 |
Product Specific Information
This antibody detects endogenous levels of total PDZD2 protein.
Target Information
Proteins containing PDZ domains frequently bind the C-termini of transmembrane receptors or ion channels. They also interact with other PDZ domain proteins and may be involved in intracellular signaling.
The PDZD2 gene encodes a protein with six PDZ domains, sharing sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, it localizes to the endoplasmic reticulum and is cleaved by a caspase to produce a secreted peptide containing two PDZ domains.
PDZD2 is upregulated in primary prostate tumors and may play a role in early prostate tumorigenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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