Thermo Fisher Scientific Thrombomodulin/CD141 (Endothelial Cell Marker) Recombinant Rabbit Monoclonal Antibody (THBD/8188R)
인간 Thrombomodulin/CD141을 표적으로 하는 재조합 토끼 단클론 항체. IHC(P) 및 IHC(PFA) 실험에 적합하며 높은 특이성과 재현성을 제공. CHO 세포 발현, Protein A/G 정제, 보존제 무첨가 액상 형태로 연구용에 최적화.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | THBD/8188R |
| Immunogen | Recombinant full-length human Thrombomodulin (CD141) protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Thrombomodulin (TM), also known as Fetomodulin (FM), endothelial anticoagulant protein, or glycoprotein P112, contains six repeated domains homologous with epidermal growth factor (EGF) and an amino terminal domain homologous to lectin-like protein. Through its accelerated activation of protein C, TM synthesis plays a crucial role in maintaining thrombo-resistance and reducing clot formation on endothelial cell surfaces. Immunohistochemical staining of formalin-fixed tissue for TM has been used in studies of various vascular tumors, meningiomas, and choriocarcinomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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