Thermo Fisher Scientific Phospho-MCM2 (Ser108) Polyclonal Antibody
MCM2 단백질의 Ser108 인산화 부위를 인식하는 rabbit polyclonal antibody. Western blot, IHC, IP 등 다양한 응용에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 시약으로, 4°C에서 보관. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:5,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:1,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:5,000 |
| Immunoprecipitation (IP) | See datasheet |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphorylated peptide representing a portion of human Minichromosomal Maintenance Deficient 2 surrounding Serine 108 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Information
MCM2 (Mini chromosome maintenance protein 2) is involved in regulating DNA replication. MCM2, also known as CDCL1, mitotin, and BM28, is a human nuclear protein crucial for the cell cycle, participating in the onset of DNA replication and cell division. It is similar to early S-phase proteins and has been mapped to chromosome 3q21. CDCL1 is considered a candidate oncogene affected by chromosomal breaks in acute myeloid leukemia (AML).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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