Thermo Fisher Scientific XPO4 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1-3 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

Assay-Dependent

-

Product Specifications

Species Reactivity

Dog, Chicken, Human, Mouse, Non-human primate, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to residues 850-950 of human Exportin-4. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:XPO4,uniProtId:Q9C0E2-1,ncbiNodeId:9606,antigenRange:850-950,antigenLength:1151,antigenImageFileName:PA1-41633_XPO4_Q9C0E2-1_Rabbit.svg,antigenImageFileNamePDP:PA1-41633_XPO4_Q9C0E2-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Protein G

Storage buffer

PBS with 0.2% gelatin

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2215471

Product Specific Information

PA1-41633 detects Exportin-4 in chicken, chimpanzee, rhesus monkey, canine, human, rat and mouse samples.

This antibody is predicted to react with bovine, xenopus, and zebrafish based on sequence homology.

Suggested positive control: Jurkat whole cell lysate.

Target Information

Nuclear transport receptors of karyopherin/importin-beta superfamily mediate various transport pathways between nucleus and cytoplasm. Exportin-4 is a novel mammalian member of this family. It is a RanGTP-binding protein consisting of N-terminal RanGTP-binding motif. It functions as a nuclear export receptor for eIF-5A and also might function as an export adapter in RNA export. It is also involved in nuclear export of Smad3 and regulation of Smad signaling.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.