Thermo Fisher Scientific Microphthalmia Transcription Factor (MITF) Monoclonal Antibody (PCRP-MITF-1D9)
Microphthalmia Transcription Factor (MITF)에 특이적인 Mouse Monoclonal Antibody로, WB, ICC/IF, Flow, IP 등 다양한 응용 가능. Human에 반응하며 Recombinant full-length MITF를 면역원으로 사용. 단백질 A/G로 정제된 액상 형태, 1 mg/mL 농도. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
| Immunoprecipitation (IP) | 1–2 µg |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PCRP-MITF-1D9 |
| Immunogen | Recombinant full-length human MITF protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Predicted to react in Chick, Mouse, Rat, Xenopus, Zebrafish.
Target Information
Mi is a basic helix-loop-helix-leucine zipper (b-HLH-ZIP) transcription factor involved in pigmentation, mast cell, and bone development. Mutations in Mi cause Waardenburg Syndrome type II in humans. In mice, loss of pigmented cells in skin, eye, and inner ear occurs, along with osteopetrosis and defects in natural killer and mast cells. Two isoforms exist, differing by 66 amino acids at the NH₂ terminus. Shorter forms are expressed in melanocytes (52 kDa and 56 kDa), while longer forms (60–70 kDa) are found in osteoclasts, B16 melanoma cells, mast cells, and heart.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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