Thermo Fisher Scientific IKK alpha Recombinant Rabbit Monoclonal Antibody (ARC0174)
IKK alpha 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot과 ELISA에 적합합니다. 인간 및 생쥐 시료에서 반응하며, 고순도의 Affinity Chromatography 정제 제품입니다. -20°C 보관, 연구용 전용 시약입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0174 |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 1–100 of human IKK alpha (NP_0012693) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.55 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849247 |
Product Specific Information
Immunogen sequence:
MERPPGLRPG AGGPWEMRER LGTGGFGNVC LYQHRELDLK IAIKSCRLEL STKNRERWCH EIQIMKKLNH ANVVKACDVP EELNILIHDV PLLAMEYCSG
Target Information
CHUK (IKK alpha) is a serine/threonine kinase involved in signal transduction and cellular communication. It is part of the cytokine-activated protein complex that regulates the NF-kappa B pathway. Together with IKK beta and the regulatory protein NEMO (IKK gamma), IKK alpha phosphorylates IkB proteins, leading to their ubiquitin-mediated degradation. This protein plays a critical role in inflammation and cell survival processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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