Thermo Fisher Scientific Phospho-IL10RA (Tyr496) Polyclonal Antibody
인간 IL10RA의 Tyr496 인산화 형태를 인식하는 폴리클로날 항체. Western blot 및 면역세포염색에 적합. 고순도 액상 형태로 제공되며, PBS/glycerol 버퍼에 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human IL10RA (Accession Q13651), corresponding to amino acid residues around phosphorylated Tyr496 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2816464 |
Product Specific Information
Antibody detects endogenous levels of IL-10R alpha only when phosphorylated at Tyrosine 496.
Target Information
The protein encoded by this gene is a receptor for interleukin 10. It is structurally related to interferon receptors and mediates the immunosuppressive signal of interleukin 10, inhibiting the synthesis of proinflammatory cytokines. This receptor promotes survival of progenitor myeloid cells through the IRS-2/PI3K/AKT pathway and activates JAK1 and TYK2 kinases via tyrosine phosphorylation. Two transcript variants have been identified: one protein-coding and one non-coding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-104991_IL10RA_Q13651-1_Rabbit.svg, PA5-104991_IL10RA_Q13651-1_Rabbit_PDP.jpeg)
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