Thermo Fisher Scientific Phospho-G3BP1 (Ser232) Polyclonal Antibody
G3BP1 단백질의 Ser232 인산화 형태를 특이적으로 인식하는 rabbit polyclonal antibody. Western blot, IHC, ICC/IF에 최적화되어 있으며, 인간, 마우스, 랫트 시료에 반응. 1 mg/mL 농도의 액상 형태로 제공되며, -20°C에서 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human G3BP1 (Accession Q13283), corresponding to amino acid residues around phosphorylated Ser232. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816459 |
Product Specific Information
This antibody detects endogenous levels of G3BP-1 only when phosphorylated at Serine 232.
Target Information
This gene encodes one of the DNA-unwinding enzymes that prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent manner. It belongs to the heterogeneous nuclear RNA-binding protein family and is involved in the Ras signal transduction pathway by binding specifically to the Ras-GTPase-activating protein via its SH3 domain. Several alternatively spliced transcript variants have been described, though the full-length nature of some remains undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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