Thermo Fisher Scientific CDC6 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.01-0.03 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide with sequence RKSQEITTNSEQRCP. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CDC6,uniProtId:Q99741-1,ncbiNodeId:9606,antigenRange:125-139,antigenLength:560,antigenImageFileName:PA5-142565_CDC6_Q99741-1_Goat.svg,antigenImageFileNamePDP:PA5-142565_CDC6_Q99741-1_Goat_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Ammonium sulfate precipitation

Storage buffer

TBS, pH 7.3, with 0.5% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2933212

Product Specific Information

This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.

Target Information

The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.