Thermo Fisher Scientific E2F3 Polyclonal Antibody
E2F3 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체. Western blot에 최적화되어 있으며, 고순도 액상 형태로 제공. 세포 주기 및 종양 억제 단백질 연구에 적합. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence DLEKLPLVEDFMCS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933209 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:8,000.
Target Information
The protein encoded by this gene is a member of the E2F family of transcription factors.
The E2F family plays a crucial role in the control of cell cycle and the action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses.
E2F proteins contain several evolutionally conserved domains, including:
- DNA binding domain
- Dimerization domain (interacts with DP transcription factors)
- Transactivation domain (acidic amino acids)
- Tumor suppressor protein association domain (within transactivation domain)
E2F3, along with E2F1 and E2F2, has an additional cyclin binding domain and binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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