Thermo Fisher Scientific CDKN2C Monoclonal Antibody (OTI6D3), TrueMAB
CDKN2C 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI6D3). Western blot에 최적화된 고특이성 항체로, 세포주기 조절 연구에 적합. Human 시료 반응성 확인. 고순도 Affinity chromatography 정제 및 안정한 PBS/BSA buffer 제공.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6D3 |
| Immunogen | Full length human recombinant protein of human CDKN2C produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by the CDKN2C gene is a member of the INK4 family of cyclin-dependent kinase inhibitors.
It interacts with CDK4 or CDK6 to prevent kinase activation, functioning as a regulator of cell cycle G1 progression.
Ectopic expression suppresses human cell growth in correlation with wild-type RB1 function.
Knockout mouse studies indicate roles in spermatogenesis regulation and tumor suppression.
Two alternatively spliced transcript variants encoding the same protein have been reported.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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