Thermo Fisher Scientific LIMP2 Recombinant Rabbit Monoclonal Antibody (12H5L1)
LIMP2 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot에 최적화되어 있습니다. 높은 특이성과 재현성을 제공하며, 로트 간 일관성이 우수합니다. 단기 4℃, 장기 -20℃ 보관 권장. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:500
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Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 12H5L1 |
| Immunogen | Protein corresponding to human LIMP2 (aa35–aa430) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2723321 |
Product Specific Information
This antibody is predicted to react with Monkey and Rabbit.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems clone specific antibody DNA sequences from immunoreactive rabbits, and individual clones are screened for optimal performance.
Advantages include:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to the rabbit immune repertoire
Target Information
High-density lipoproteins (HDLs) play a critical role in cholesterol metabolism, with plasma concentrations inversely correlated with atherosclerosis risk.
SR-BI and SR-BII are alternatively spliced products of a single gene. SR-BII differs from SR-BI in the C-terminal cytoplasmic domain and binds HDL with approximately 4-fold lower efficiency.
SR-BII is abundant in mouse tissues expressing SR-BI, including liver, adrenal glands, and testes. It may function as an HDL receptor mediating selective lipid transfer between HDL and cells. The relative expression of SR-BI and SR-BII provides a mechanism for regulating lipid transfer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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