Thermo Fisher Scientific PDCD1 Monoclonal Antibody (OTI18H9), TrueMAB
인간 PDCD1 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 유세포분석에 사용 가능. TrueMAB 형식으로 높은 특이성과 재현성을 제공. 액상 형태이며 -20°C 보관 권장. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Flow Cytometry (Flow)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI18H9 |
| Immunogen | Full length human recombinant PDCD1 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cell-mediated immune responses are initiated by T lymphocytes that are stimulated by peptides bound to MHC molecules on antigen-presenting cells (APC). Activated T cells express inhibitory receptors such as PD-1 (also known as PDCD-1), which mediate suppression signals upon binding to ligands PDL-1 and PDL-2. These interactions inhibit immune activation in the absence of danger signals such as LPS. PD1-deficient mice show hyperactivated immune systems and autoimmune diseases. Although PD-1 has a predicted molecular weight, it often migrates at a higher molecular weight in SDS-PAGE.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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