Thermo Fisher Scientific TNNI3 Monoclonal Antibody (OTI3B4), TrueMAB
Cardiac Troponin I를 표적으로 하는 인간 반응성 Mouse IgG2b 단일클론 항체. Western blot에 1:2,000 희석 비율로 검증됨. Affinity chromatography로 정제된 액상 형태로, 안정적인 PBS/BSA/glycerol 버퍼에 보관. 심근 손상 연구용으로 적합.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific TNNI3 Monoclonal Antibody (OTI3B4), TrueMAB
Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3B4 |
| Immunogen | Recombinant protein expressed in E. coli corresponding to amino acids 1–210 of human TNNI3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cardiac Troponin I (TnI, Troponin I, Cardiac-specific troponin I) is an integral inhibitory protein in cardiac muscle, forming a complex with troponin C (TnC) and troponin T (TnT). TnT binds to tropomyosin, forming a troponin–tropomyosin complex anchored by TnI binding to actin within thin filaments. Calcium binding to TnC induces a structural change that releases the inhibitory region of TnI, enabling myosin attachment and muscle contraction. Measurement of blood TnI and TnT levels serves as a diagnostic indicator for cardiac muscle damage, aiding differentiation between angina and myocardial infarction. Cardiac Troponin I also inhibits angiogenesis and mutations in its gene are associated with familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 없음)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.