Thermo Fisher Scientific CD20/MS4A1 (B-Cell Marker) Monoclonal Antibody (93-1B3)
인간 CD20/MS4A1 B세포 마커를 인식하는 Mouse IgG1 단클론 항체로, ICC/IF, Flow Cytometry 및 Functional Assay에 사용 가능. 비결합형 액상 형태이며 Protein A/G로 정제됨. 연구용으로만 사용.
- 카탈로그번호
- 931-MSM5-Px (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD20/MS4A1 (B-Cell Marker) Monoclonal Antibody (93-1B3)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
| Functional Assay | Assay-dependent |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 93-1B3 |
| Immunogen | Stimulated human leukocytes |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD20 is a non-glycosylated surface phosphoprotein with a molecular weight range of 33–37 kDa depending on phosphorylation. It is expressed on mature and most malignant B cells, a subpopulation of T lymphocytes, and follicular dendritic cells. CD20 expression is synchronous with surface IgM and regulates calcium conductance, cell cycle progression, and B-cell proliferation.
It is associated with lipid rafts, and its interaction with BCR (B cell antigen receptor) changes upon extracellular triggering. CD20 remains at the cell surface after BCR endocytosis, making it a useful target for antibody-mediated B-cell depletion.
Diseases associated with CD20 dysfunction include Ms4a1-related common variable immune deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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