Thermo Fisher Scientific 53BP1 Recombinant Superclonal Antibody (7HCLC)

Applications

Immunocytochemistry (ICC/IF)

• Tested Dilution: 1:100

Product Specifications

Product Specific Information

This antibody is predicted to react with Mouse, Rat, and Bovine.

Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They combine multiple recombinant monoclonal antibodies, providing the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies, and the consistency of recombinant production.
These antibodies recognize multiple epitope sites, offering higher detection sensitivity for low-abundance targets. Each lot contains a defined mixture of light and heavy chains, ensuring reproducibility and eliminating biological variability seen in traditional polyclonal antibodies.
Note: Formerly called “Recombinant Polyclonal Antibody”, now rebranded as “Recombinant Superclonal™ Antibody”. Product and performance remain unchanged.

Target Information

53BP1 (P53-binding protein 1) plays a critical role in tumor suppression and is a substrate of ATM kinase. Upon DNA damage, 53BP1 is phosphorylated and localizes to double-strand break sites. It is involved in checkpoint signaling during mitosis, enhances TP53-mediated transcriptional activation, and supports DNA repair to maintain genomic stability.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.