Thermo Fisher Scientific MHC Class II Monoclonal Antibody (PF8J-9B)
고양이 MHC Class II 베타 체인 인식 단일클론 항체로 다양한 면역분석(WB, ICC/IF, Flow, ELISA)에 사용 가능. 단백질 A로 정제된 액상 형태이며 1 mg/mL 농도. 항원제시세포 및 활성화 T세포 등에서 발현된 MHC Class II 검출에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
Immunocytochemistry (ICC/IF)
- Tested Dilution: Assay-dependent
Flow Cytometry (Flow)
- Tested Dilution: Assay-dependent
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Cat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PF8J-9B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS |
| Contains | <0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745442 |
Product Specific Information
This antibody recognizes an epitope within the beta chain region of cat MHC class II molecule, expressed by antigen-presenting cells, B cells, monocytes, and activated T lymphocytes.
Target Information
MHC (major histocompatibility complex) class II molecules are transmembrane glycoproteins expressed on the surface of professional antigen-presenting cells such as macrophages, dendritic cells, and B cells.
Before their exposition on the cell surface, the MHC class II molecules react with endocytosed exogenous antigens, which are then presented to the T cells.
The antigen-binding groove between MHC class II alpha and beta chain is open at both ends and is 15–24 amino acid residues long.
HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem mass spectrometry.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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