Thermo Fisher Scientific MHC Class II Monoclonal Antibody (PF6J-6D)
고양이 MHC Class II 분자를 인식하는 단클론 항체로, 항원제시세포 및 활성화된 T 림프구 연구에 적합함. Western blot, IHC, Flow cytometry, ELISA 등 다양한 면역분석에 사용 가능. 단백질 A로 정제된 액상 형태이며 장기보관 시 -20°C 권장.
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Applications
- Western Blot (WB): Assay-dependent
- Immunohistochemistry (Paraffin) (IHC (P)): Assay-dependent
- Flow Cytometry (Flow): Assay-dependent
- ELISA (ELISA): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Cat |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PF6J-6D |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | <0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745441 |
Product Specific Information
This antibody recognizes an epitope within the beta chain region of cat MHC class II molecules which are expressed by antigen presenting cells, B cells, monocytes, and activated T lymphocytes.
Target Information
MHC (major histocompatibility complex) class II molecules are transmembrane glycoproteins expressed on the surface of professional antigen-presenting cells such as macrophages, dendritic cells, and B cells. Before their exposition on the cell surface, the MHC class II molecules react with endocytosed exogenous antigens, which are then presented to T cells.
The antigen-binding groove between MHC class II alpha and beta chain is open at both ends and is 15–24 amino acid residues long.
HLA and MHC antibodies play a significant role in immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem mass spectrometry.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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