Thermo Fisher Scientific GRASP1 Polyclonal Antibody
Rabbit polyclonal antibody targeting Human GRASP1 protein. Validated for Western blot applications with high specificity. Suitable for human and mouse samples. Supplied as liquid, unconjugated form with antigen affinity purification. For research use o...
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Applications
- Western Blot (WB): Tested dilution 1:1,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 343–600 of Human GRASP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.96 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2549627 |
Product Specific Information
- Recommended positive controls: 293T, A431, HeLa, HepG2, mouse brain
- Predicted reactivity: Mouse (94%), Rat (93%), Bovine (95%)
- Store as a concentrated solution. Centrifuge briefly before opening the vial.
Target Information
PDZ domain-containing proteins, such as PSD-95 and GRIP, play key roles in glutamate receptor plasticity. GRIP-associated proteins (GRASPs) bind to distinct PDZ domains within GRIP and regulate glutamate receptor function. GRASP-1 is a neuronal rasGEF associated with GRIP and AMPA receptors in vivo. Studies suggest that GRASP-1 regulates neuronal ras signaling and contributes to AMPA receptor distribution through NMDA receptor activity.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information: www.P65Warnings.ca.gov
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: PA5-32154_GRASP1_Q4V328-1_Rabbit.svg, PA5-32154_GRASP1_Q4V328-1_Rabbit_PDP.jpeg)
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