Thermo Fisher Scientific ALDH1A1 Polyclonal Antibody
Rabbit polyclonal antibody against human ALDH1A1. Validated for WB, IHC(P), and ICC/IF. High specificity and sensitivity with antigen affinity purification. Supplied as liquid form, 1 mg/mL concentration, stored at -20°C. For research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–232 of Human ALDH1A1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2549632 |
Product Specific Information
- Recommended positive control: A549
- Predicted reactivity: Mouse (85%), Rat (84%), Dog (88%), Rabbit (88%), Chicken (81%), Sheep (92%), Chimpanzee (100%), Bovine (90%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
ALDH1A1 belongs to the aldehyde dehydrogenase family of proteins. It catalyzes the oxidation of aldehydes in the major oxidative pathway of alcohol metabolism. Two major liver isoforms exist—cytosolic and mitochondrial—distinguished by electrophoretic mobility and subcellular localization. Most Caucasians express both isozymes, while approximately 50% of Orientals express only the cytosolic isozyme, lacking the mitochondrial form. This difference may contribute to the higher frequency of acute alcohol intoxication among Orientals.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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