Thermo Fisher Scientific RED Polyclonal Antibody
Thermo Fisher Scientific의 RED Polyclonal Antibody는 인간 단백질 RED를 인식하는 Rabbit IgG 항체로, WB, IHC, ICC/IF에 사용 가능합니다. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 1–45 of RED (Uniprot ID: Q13123) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C (short term). For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11152931 |
Product Specific Information
- Recommended positive controls: THP-1, HL-60
- Predicted reactivity: Mouse (100%), Rat (100%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
IMP-3 (Insulin-like growth factor-II mRNA-binding protein-3), also known as KOC or L523S, is a member of the IGF-II mRNA-binding protein family. It is expressed during embryogenesis and in various malignancies.
IMP-3 is expressed in malignant melanoma but not in benign nevi, even when dysplastic features are present. It is found in a significantly higher proportion of melanomas than Spitz nevi and more in metastatic melanomas than in thin melanomas.
IMP-3 appears to be involved in melanoma progression and may regulate tumor biologic behavior.
Safety and Regulatory Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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