Thermo Fisher Scientific MVP Polyclonal Antibody
인간 MVP 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF 등 다양한 응용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보존. 약물 내성 연구 및 세포 내 단백질 수송 연구에 적합.
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Thermo Fisher Scientific MVP Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MVP. Recombinant protein control fragment (Product #RP-101753). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2789172 |
Product Specific Information
Immunogen sequence:
VFEEVLDLVD AVILTEKTAL HLRARRNFRD FRGVSRRTGE EWLVTVQDTE AHVPDVHEEV LGVVPITTLG PHNYCVILDP VGPDGKNQLG QKRVVKGEKS FFLQPGEQLE QGIQDVYVLS
Target Information
This gene encodes the major vault protein (MVP), a lung resistance-related protein. Vaults are multi-subunit structures involved in nucleo-cytoplasmic transport. MVP mediates drug resistance, possibly via a transport process. It is widely distributed in normal tissues and overexpressed in multidrug-resistant cancer cells, serving as a potential marker of clinical drug resistance. The gene produces two transcripts using alternative exon 2 sequences, but both share the same open reading frame.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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