Thermo Fisher Scientific Livin Monoclonal Antibody (88C570)
Livin 단백질을 표적하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody (Clone 88C570). Western blot과 Immunocytochemistry에 최적화. 인간 시료 반응성, 비결합형 액상 형태, Protein G 정제, 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 2–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 88C570 |
| Immunogen | Recombinant human livin protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2537715 |
Product Specific Information
Suggested positive control: U266, HeLa, Jurkat.
Target Information
The inhibitor of apoptosis (IAP) family of proteins regulates programmed cell death triggered by various stimuli. All IAPs have at least one baculovirus IAP repeat (BIR) motif that is essential for their anti-apoptotic activity.
Livin (also known as ML-IAP) is a novel human IAP family member containing a single BIR domain and a COOH-terminal RING finger domain. The Livin gene has two splicing variants (298 and 280 amino acids), both containing a BIR and RING domain. Both isoforms inhibit TNFα-induced apoptosis in Jurkat cells. Livin expression is low in adult tissues but relatively higher in developmental tissues and many cancer cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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