
Thermo Fisher Scientific WDR74 Polyclonal Antibody
Thermo Fisher Scientific의 WDR74 Polyclonal Antibody는 인간 및 랫트 시료에서 WDR74 단백질 검출용으로 최적화된 rabbit IgG 폴리클로날 항체입니다. Western blot에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | An 18 amino acid peptide near the amino terminus of human NSA1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage, store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11154827 |
Product Specific Information
- A suggested positive control is rat liver tissue lysate.
- PA5-20925 can be used with blocking peptide PEP-1039.
Target Information
The yeast nucleolar protein NOP7 is necessary for the maturation of 66S preribosomes and interacts with numerous other proteins.
One such protein is an essential, conserved WD repeat protein, NOP seven-associated protein 1 (NSA1), that is also required for the yeast 66S ribosome assembly.
NSA1 is also associated with the AAA ATPase Rix7, and release of NSA1 from a novel late nucleolar pre-60S requires the Rix7 function.
NSA1 has also been found upregulated in mammalian cancer cells, suggesting it may also play a role in cell proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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