Thermo Fisher Scientific NFAT5 Polyclonal Antibody
Rabbit polyclonal antibody targeting human NFAT5 for Western blot applications. Recognizes synthetic peptide from NFAT5 middle region. High cross-species homology and affinity-purified for reliable performance. Supplied in PBS with sucrose and sodium a...
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Applications
- Western Blot (WB): 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human NFAT5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2884175 |
Product Specific Information
- Immunogen sequence: PGQPQNEGQP PVTTLLSQQM PENSPLASSI NTNQNIEKID LLVSLQNQGN
- Storage recommendations:
- Short-term: Store at 2–8°C up to 1 week
- Long-term: Store at -20°C in small aliquots to prevent freeze-thaw cycles
- Predicted homology: Cow 93%; Dog 86%; Guinea Pig 100%; Horse 86%; Human 100%; Rabbit 93%; Rat 100%
Target Information
The nuclear factor of activated T-cells (NFAT) transcription complex is required for the expression of proteins that collectively regulate the immune response. Four NFAT proteins—NFAT1 (NFATp/NFATc2), NFAT2 (NFATc/NFATc1), NFAT3, and NFAT4 (NFATx/NFATc3)—are encoded by separate genes and expressed as splice variants. These proteins show limited sequence similarity with the Dorsal/Rel/NFkB family of transcription factors. NFAT5 differs from isoforms 1–4 in lacking Fos/Jun contact sites and its localization is not calcineurin-dependent.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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