Thermo Fisher Scientific FLASH Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1733-1982 of human CASP8AP2 (NP_0362471) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:FLASH,uniProtId:Q9UKL3-1,ncbiNodeId:9606,antigenRange:1733-1982,antigenLength:1982,antigenImageFileName:PA5-90692_FLASH_Q9UKL3-1_Rabbit.svg,antigenImageFileNamePDP:PA5-90692_FLASH_Q9UKL3-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.85 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2806179

Product Specific Information

Immunogen sequence: TVGAFIDLTQ DASSEAKSEG NHPALAVEDL GCGVIQVDED NCKEEKAQVA NRPLKCIVEE TYIDLTTESP SSCEVKKDEL KSEPGSNCDN SELPGTLHNS HKKRRNISDL NHPHKKQRKE TDLTNKEKTK KPTQDSCENT EAHQKKASKK KAPPVTKDPS SLKATPGIKD SSAALATSTS LSAKNVIKKK GEIIILWTRN DDREILLECQ KRGPSFKTFA YLAAKLDKNP NQVSERFQQL MKLFEKSKCR; Positive Samples: U-87MG, K-562; Cellular Location: Cytoplasm, Mitochondrion, Nucleus, PML body

Target Information

This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.