Thermo Fisher Scientific ATP2A1 Monoclonal Antibody (3H4)
ATP2A1 단백질을 인식하는 Mouse IgG3 단클론 항체로 ELISA에 적합. 인간 시료 반응성. 비결합형 액상 형태이며 -20°C 보관. SERCA1 ATPase 연구용으로 사용.
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Applications
- ELISA (ELISA)
Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG3, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3H4 |
| Immunogen | ATP2A1 (NP_775293, 522–612 a.a) partial recombinant protein with GST tag. MW of GST tag alone is 26 kDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
IDRCNYVRVG TTRVPLTGPV KEKIMAVIKE WGTGRDTLRC LALATRDTPP KREEMVLDDS ARFLEYETDL TFVGVVGMLD PPRKEVTGSI Q
Target Information
ATP-dependent calcium pumps maintain low cytoplasmic free calcium concentrations. These pumps in intracellular organelles are encoded by a family of structurally related enzymes called sarcoplasmic or endoplasmic reticulum calcium (SERCA) ATPases.
- SERCA1 gene: Exclusively expressed in type II (fast) skeletal muscle.
- SERCA2 gene: Tissue-dependent processing generates SERCA2a (muscle-specific, type I/slow skeletal, cardiac, smooth muscle) and SERCA2b (expressed in all cell types).
- SERCA3 gene: Found in non-muscle cells and less characterized.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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