Thermo Fisher Scientific TNNI2 Polyclonal Antibody
Human TNNI2 단백질에 특이적인 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 안정한 액상 형태로 제공. 연구용으로 근육 및 종양 관련 단백질 분석에 적합.
- 판매단위
- pk
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Thermo Fisher Scientific TNNI2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,500–1:5,000 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TNNI2. Recombinant protein control fragment (Product #RP-103237). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.45 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2791424 |
Product Specific Information
Immunogen sequence:
ELEKEESRRE AEKQNYLAEH CPPLHIPGSM SEVQELCKQL HAKIDAAEEE KYDMEVRVQK TSK
Target Information
This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C, and troponin I subunits. The troponin complex, along with tropomyosin, regulates calcium-dependent striated muscle contraction.
Mouse studies show that this component is also present in vascular smooth muscle and may play a role in smooth muscle regulation.
In addition to muscle tissues, this protein is found in corneal epithelium and cartilage where it inhibits angiogenesis and tumor growth, and in mammary gland where it acts as a co-activator of estrogen receptor-related receptor alpha.
Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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