Thermo Fisher Scientific ROR gamma Polyclonal Antibody
ROR gamma 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간 샘플에서 검출 가능하며 IHC(P) 등 다양한 연구용 애플리케이션에 적합. 장기 보관 시 -20°C에서 안정적으로 유지되며, 면역조직화학 연구에 유용.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 22 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 19 amino acid peptide from ligand-binding domain of human ROR gamma |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2180319 |
Product Specific Information
PA1-32610 detects ROR gamma from human samples.
Target Information
ROR gamma is a 560 amino acid DNA-binding transcription factor belonging to the ROR/RZR orphan nuclear receptor subfamily. It is a ligand-activated transcription factor essential for lymphoid organogenesis (lymph nodes and Peyer’s patches) and plays a regulatory role in apoptosis during thymopoiesis.
ROR gamma inhibits Fas ligand and IL2 expression and directs differentiation of proinflammatory IL-17+ T helper cells. It shares 50–51% sequence identity with RORA and RORB, and is 88% identical to mouse ROR gamma. Highly expressed in skeletal muscle and at lower levels in other tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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