Thermo Fisher Scientific Arginase 2 Recombinant Rabbit Monoclonal Antibody (1Y5U3)
Recombinant Rabbit Monoclonal Antibody targeting human Arginase 2 (ARG2). Western blot, IHC, ELISA에 적합하며 고특이성, 고재현성 제공. HEK293 발현 시스템 기반, 액상 형태로 -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 1Y5U3 |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 255–354 of human Arginase 2 (ARG2) (P78540) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911830 |
Product Specific Information
- Positive test controls: 293T cells
- Subcellular location: Mitochondrion
Immunogen sequence:
FDPTLAPATG TPVVGGLTYR EGMYIAEEIH NTGLLSALDL VEVNPQLATS EEEAKTTANL AVDVIASSFG QTREGGHIVY DQLPTPSSPD ESENQARVRI
Target Information
Arginase catalyzes the hydrolysis of arginine to ornithine and urea. Two isoforms of mammalian arginase (types I and II) differ in tissue distribution, subcellular localization, and physiologic function. The type II isoform, encoded by this gene, is mitochondrial and expressed in extra-hepatic tissues such as kidney. It may play a role in nitric oxide and polyamine metabolism. Transcript variants using alternative polyadenylation sites have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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