Thermo Fisher Scientific Arginase 2 Recombinant Rabbit Monoclonal Antibody (1Y5U3)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

1Y5U3

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 255-354 of human Arginase 2 (ARG2) (P78540). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Arginase 2,uniProtId:P78540-1,ncbiNodeId:9606,antigenRange:255-354,antigenLength:354,antigenImageFileName:MA5-42689_Arginase_2_P78540-1_Rabbit.svg,antigenImageFileNamePDP:MA5-42689_Arginase_2_P78540-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2911830

Product Specific Information

Positive test controls include: 293T. The target is usually found in the following locations: Mitochondrion.

Immunogen sequence: FDPTLAPATG TPVVGGLTYR EGMYIAEEIH NTGLLSALDL VEVNPQLATS EEEAKTTANL AVDVIASSFG QTREGGHIVY DQLPTPSSPD ESENQARVRI

Target Information

Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.