Thermo Fisher Scientific Human IRF7 Synthetic Peptide
Human IRF7 단백질의 C-말단 14개 아미노산 서열로 구성된 합성 펩타이드. 항체 차단 실험용으로 사용 가능하며, IRF7 관련 면역 반응 연구에 적합. 액상 형태, 200 µg/mL 농도, PBS(pH 7.2) 용액에 0.1% BSA 및 0.02% sodium azide 포함.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
Product Specific Information
This peptide corresponds to 14 amino acids near the carboxy terminus of human IRF7.
PEP-0414 can be used as a blocking peptide with polyclonal antibody PA5-20280.
Target Information
Interferons (IFNs) are involved in numerous immune interactions during viral infections and play key roles in the induction and regulation of innate and adaptive antiviral mechanisms.
During infection, host-virus interactions signal downstream molecules such as transcription factors like IFN regulatory factor-3 (IRF3), which stimulate transcription of IFN-α/β genes.
IRF7 contributes to the transcriptional activation of virus-inducible genes, including interferon beta chain genes, and plays a major role in the innate immune pathway by interacting with Toll-like receptor (TLR) adaptor proteins MyD88 and Tirp/TRAM, functioning as an intermediate in TLR4 and TLR9 signaling.
There are at least four differentially spliced isoforms of IRF7, though their functions are not yet clearly established.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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