Thermo Fisher Scientific ERCC1 Polyclonal Antibody
ERCC1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC/IF에 사용 가능. 인간 및 랫드 반응성 확인. 항원 친화 크로마토그래피로 정제된 액상 형태로 제공되며, DNA 손상 복구 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human ERCC1 (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2735768 |
Product Specific Information
- Positive Control: 293T, A431, HeLa, HepG2, PC-12, Rat2
- Predicted Reactivity: Mouse (86%), Pig (87%), Chimpanzee (100%), Bovine (87%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
ERCC1 is a non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5′ incision during DNA repair. It acts with SLX4 in the first step of interstrand cross-link (ICL) repair and participates in processing DNA structures that may cause cytokinesis failure. ERCC1 is also required for homology-directed repair (HDR) of DNA double-strand breaks in conjunction with SLX4. (Source: UniProt)
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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