Thermo Fisher Scientific DIO2 Polyclonal Antibody
Rabbit polyclonal antibody against human DIO2 protein. Validated for ICC/IF applications with high specificity. Supplied unconjugated in liquid form, purified by antigen affinity chromatography. Suitable for research use only, not for diagnostic purposes.
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Thermo Fisher Scientific DIO2 Polyclonal Antibody
Applications
- Immunocytochemistry (ICC/IF): Tested dilution 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human DIO2. Recombinant protein control fragment (Product #RP-106163) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664293 |
Product Specific Information
Immunogen sequence:
EWRRMLTSEGL RCVWKSFLLD AYKQVKLGED APNSSVVHVS STEGGDNSGN GTQEKIAEGA TCHLLDFASP ERP
Highest antigen sequence identity to the following orthologs:
- Mouse: 80%
- Rat: 51%
Target Information
The protein encoded by this gene belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine via outer ring deiodination to bioactive 3,3’,5-triiodothyronine. The 3’ UTR of Sec-containing genes includes a stem-loop structure (sec insertion sequence) necessary for recognition of UGA as a Sec codon rather than a stop signal. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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