Thermo Fisher Scientific mGluR3 Polyclonal Antibody
Thermo Fisher Scientific의 mGluR3 Polyclonal Antibody는 Rat mGluR3(aa 118-126)에 대응하는 합성 펩타이드로부터 제작된 Rabbit IgG 항체입니다. Western blot에 적합하며, Rat 뇌 조직에서 높은 특이성을 보입니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific mGluR3 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide TKVDEAEYM, corresponding to amino acids 118–126 of Rat metabotropic Glutamate Receptor 3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | Store at 4°C for short term. For long-term storage, keep at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_1957779 |
Product Specific Information
- Recommended positive controls: Rat cerebellar and cortical membrane.
Target Information
Glutamate is the main excitatory neurotransmitter in the brain. It acts on ligand-gated receptor channels such as NMDA, AMPA, and kainate receptors, which mediate fast excitatory synaptic transmission.
Recently, glutamate has been shown to regulate enzymes producing second messengers via specific G-protein-coupled receptors, known as metabotropic glutamate receptors (mGluRs).
Group I receptors (mGluR1a, mGluR5) stimulate phospholipase C, increasing phosphoinositide turnover and calcium release.
Group II and III receptors (including mGluR2 and mGluR3) inhibit adenylyl cyclase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: PA1-29424_mGluR3_P31422-1_Rabbit.svg, PA1-29424_mGluR3_P31422-1_Rabbit_PDP.jpeg)
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