Thermo Fisher Scientific YARS Polyclonal Antibody

Thermo Fisher Scientific YARS Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

• Recommended positive control: H1299
• Predicted reactivity: Mouse (93%), Rat (90%), Chicken (82%), Bovine (92%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution.
Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts: an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme.
The N-terminal fragment acts as an interleukin-8-like cytokine, whereas the released C-terminal fragment functions as an EMAP II-like cytokine.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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