Thermo Fisher Scientific Cytokeratin 5/14 Monoclonal Antibody (LH8)

Applications

Tested Dilution

Publications

Immunohistochemistry (IHC)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgM

Class

Monoclonal

Type

Antibody

Clone

LH8

Immunogen

The 50,000 Mr band (including K14 )cut from an SDS-polyacrylamide gel and Triton X-100 extracted cytoskeleton pellet from cultured human foreskin keratinocytes. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Cytokeratin 5/14,uniProtId:P02533-1,ncbiNodeId:9606,antigenRange:1-472,antigenLength:472,antigenImageFileName:MA1-90930_Cytokeratin_514_P02533-1_House_mouse.svg,antigenImageFileNamePDP:MA1-90930_Cytokeratin_514_P02533-1_House_mouse_PDP.jpeg,sortOrder:1},{targetFamily:Cytokeratin 5/14,uniProtId:P13647-1,ncbiNodeId:9606,antigenRange:1-590,antigenLength:590,antigenImageFileName:MA1-90930_Cytokeratin_514_P13647-1_House_mouse.svg,antigenImageFileNamePDP:MA1-90930_Cytokeratin_514_P13647-1_House_mouse_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.8 mg/mL

Purification

IgG fraction

Storage buffer

PBS

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_1955730

Product Specific Information

MA1-90930 detects Cytokeratin 5 + 14 from human samples.

Target Information

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.