
Thermo Fisher Scientific Cytokeratin 5/14 Monoclonal Antibody (LH8)
인체 시료의 Cytokeratin 5/14 단백질을 검출하는 마우스 단클론 항체입니다. IHC 분석에 적합하며, 0.8 mg/mL 농도의 액상 시약으로 제공됩니다. PBS 버퍼에 보존제가 포함되지 않았으며, 단기 4°C, 장기 -20°C 보관이 권장됩니다.
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Applications
- Immunohistochemistry (IHC): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgM |
| Class | Monoclonal |
| Type | Antibody |
| Clone | LH8 |
| Immunogen | The 50,000 Mr band (including K14) cut from an SDS-polyacrylamide gel and Triton X-100 extracted cytoskeleton pellet from cultured human foreskin keratinocytes. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.8 mg/mL |
| Purification | IgG fraction |
| Storage buffer | PBS |
| Contains | No preservative |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1955730 |
Product Specific Information
MA1-90930 detects Cytokeratin 5 + 14 from human samples.
Target Information
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues.
This type II cytokeratin is specifically expressed in the basal layer of the epidermis along with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex.
The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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