Thermo Fisher Scientific RM30 Polyclonal Antibody
Thermo Fisher Scientific의 RM30 폴리클로날 항체는 인간, 마우스, 랫트 시료에서 MRPL30 단백질을 검출합니다. Western blot 및 IHC(P) 실험에 적합하며, 액상 형태로 1 mg/mL 농도로 제공됩니다. 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 보장합니다.
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Thermo Fisher Scientific RM30 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MRPL30 (Accession Q8TCC3), corresponding to amino acid residues W31–W81 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852860 |
Product Specific Information
Antibody detects endogenous levels of total MRPL30.
Target Information
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and are essential for protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit, with an estimated 75% protein to rRNA ratio—opposite to prokaryotic ribosomes. Unlike prokaryotic ribosomes, mammalian mitoribosomes lack a 5S rRNA. The proteins comprising mitoribosomes vary greatly among species, making sequence homology recognition difficult. The MRPL30 gene encodes a 39S subunit protein, with multiple transcript variants due to alternative splicing. Pseudogenes corresponding to this gene are found on chromosomes 6p and 12p, and read-through transcription occurs between this gene and the neighboring LIPT1 gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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